Search on:
AGGRECANASE 1
Descriptors Found:
1
Displaying:
1 .. 1
1 / 1
DeCS
Descriptor
English
:
ADAMTS4 Protein
Descriptor
Spanish
:
Proteína ADAMTS4
Descriptor
Portuguese
:
Proteína ADAMTS4
Synonyms
English
:
A Disintegrin And Metalloproteinase With Thrombospondin Motifs 4 Protein
ADAMTS-4 Protein
Aggrecanase-1
ADAMTS 4 Protein
Aggrecanase 1
Tree Number:
D08.811.277.656.675.374.102.500.844
D09.400.430.500.500.844
D12.776.395.033.500.844
D12.776.860.300.085.844
Definition
English
:
An ADAMTS protease
similar
to
ADAMTS5 PROTEIN
. It contains a single C-terminal
thrombospondin
(TS) motif and cleaves AGGRECAN in
CARTILAGE
. It may also be involved in the destruction of aggrecan in
ARTHRITIS.
History Note
English
:
2017 (1999)
Allowable Qualifiers
English
:
AD
administration & dosage
AE
adverse effects
AN
analysis
AI
antagonists & inhibitors
BI
biosynthesis
BL
blood
CF
cerebrospinal fluid
CS
chemical synthesis
CH
chemistry
CL
classification
DF
deficiency
DE
drug effects
EC
economics
GE
genetics
HI
history
IM
immunology
IP
isolation & purification
ME
metabolism
PK
pharmacokinetics
PD
pharmacology
PH
physiology
PO
poisoning
RE
radiation effects
SE
secretion
ST
standards
SD
supply & distribution
TU
therapeutic use
TO
toxicity
UL
ultrastructure
UR
urine
Record Number:
56488
Unique Identifier:
D000071121
Occurrence in VHL
:
Similar:
DeCS
CID-10
LILACS